GNGT2

Across TCGA cell cohorts, GNGT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,445 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GNGT2-associated GO terms across cancer lineages are Cellular hyperosmotic response, Detection of external stimulus, and Cellular response to reactive nitrogen species. Each is linked with GNGT2 in more than 5 cancer types. Because this analysis shows association rather than direction, both GNGT2-to-partner and partner-to-GNGT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular hyperosmotic response grouped by GNGT2-low versus GNGT2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GNGT2→partner) and Y-score (partner→GNGT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Cellular hyperosmotic response →	+0.120	+1.111	<.001	.001	3	6
BONE	Detection of external stimulus →	-0.102	-2.672	.002	<.001	3	6
LARGE_INTESTINE	Cellular response to reactive nitrogen species →	+0.133	+0.306	<.001	.003	3	5
LARGE_INTESTINE	Cellular response to nitric oxide →	+0.133	+0.306	<.001	.003	3	5
LARGE_INTESTINE	Dentinogenesis →	+0.830	+0.355	.001	.005	3	5
BONE	Detection of abiotic stimulus →	-0.096	-2.015	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,445 associations by consensus.

Cellular hyperosmotic response by GNGT2 expression — SOFT_TISSUE

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