GNG5

Across TCGA patient cohorts, GNG5 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,744 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GNG5-associated proteins across cancer lineages are BIN1, ALDH5A1, and TIMM13. Each is linked with GNG5 in more than 3 cancer types. Because this analysis shows association rather than direction, both GNG5-to-partner and partner-to-GNG5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNG5 versus BIN1 in GBM, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNG5→partner) and Y-score (partner→GNG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BIN1 →	-0.608	-0.509	<.001	<.001	3	3
BRCA	ALDH5A1 →	-0.815	-0.717	<.001	<.001	3	3
LUAD	TIMM13 →	-0.431	-0.374	<.001	.001	3	3
GBM	ECE1 →	+0.387	+0.472	<.001	<.001	3	3
BRCA	AKAP13_S790 →	+1.149	+0.899	<.001	<.001	3	3
BRCA	PDK2 →	-0.484	-0.616	.002	<.001	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,744 associations by consensus.

GNG5 vs BIN1 — GBM

Explore this scatter interactively →