GNG13

Across TCGA patient cohorts, GNG13 mutation is significantly associated with the RNA expression of many other genes, with 64 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible GNG13-associated genes across cancer lineages are RBX1P1, MRPL51P2, and RPS29P27. Each is linked with GNG13 in more than 1 cancer types. Because this analysis shows association rather than direction, both GNG13-to-partner and partner-to-GNG13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBX1P1 grouped by GNG13-low versus GNG13-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNG13→partner) and Y-score (partner→GNG13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RBX1P1 →	+0.129	+7.640	<.001	.009	3	1
BLCA	MRPL51P2 →	+0.114	+7.640	<.001	.009	3	1
BLCA	RPS29P27 →	+0.234	+7.640	<.001	.009	3	1
BLCA	RNA5SP337 →	+0.333	+7.640	<.001	.009	3	1
LGG	RNU1-15P →	+0.274	+7.977	<.001	.007	3	1
LGG	POTEB →	+0.019	+7.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 64 associations by consensus.

RBX1P1 by GNG13 expression — BLCA

Explore this box plot interactively →