GNG12-AS1

Across TCGA pan-cancer cohorts, GNG12-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated GNG12-AS1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher GNG12-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated GNG12-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and KIRC show a favorable association.

UCS, KIRC, and ACC are the cancer types where GNG12-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	II,III,IV	0.551	0.085	<.001	110	view →
KIRC	OS	Median	All	0.712	0.559	<.001	107	view →
ACC	DFS	Quartile	II,III,IV	0.247	0.787	.001	65	view →
BRCA	OS	Tertile	All	0.963	0.901	<.001	62	view →
LGG	DFS	Median	All	0.656	0.820	<.001	51	view →
STAD	OS	Quartile	All	0.350	0.720	<.001	50	view →
LUSC	DFS	Tertile	III,IV	0.235	0.935	<.001	38	view →
ESCA	DFS	Median	All	0.626	0.436	.003	27	view →
BLCA	OS	Quartile	II,III,IV	0.488	0.678	.004	26	view →
CESC	OS	Quartile	III,IV	0.401	0.852	.043	12	view →
KIRP	DFS	Quartile	All	0.778	0.946	.004	10	view →
THCA	DFS	Tertile	IV	0.492	1.000	.004	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

GNG12-AS1–UCS (DFS)

Open the UCS breakdown →