GNG11

Across TCGA patient cohorts, GNG11 protein abundance is significantly associated with the RNA expression of many other genes, with 15,327 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GNG11-associated genes across cancer lineages are LYVE1, ABCA8, and DIPK2B. Each is linked with GNG11 in more than 6 cancer types. Because this analysis shows association rather than direction, both GNG11-to-partner and partner-to-GNG11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNG11 versus LYVE1 in OV, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNG11→partner) and Y-score (partner→GNG11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LYVE1 →	+1.628	+0.906	.001	<.001	3	7
BRCA	ABCA8 →	+1.502	+0.542	<.001	<.001	3	7
CCRCC	DIPK2B →	+1.118	+0.623	<.001	<.001	3	7
CCRCC	EMCN →	+1.580	+0.613	<.001	<.001	3	7
CCRCC	S1PR1 →	+1.124	+0.601	<.001	<.001	3	7
HNSC	CASQ2 →	+1.980	+0.347	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,327 associations by consensus.

GNG11 vs LYVE1 — OV

Explore this scatter interactively →