GNG11

Across TCGA cell cohorts, GNG11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,212 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GNG11-associated GO terms across cancer lineages are Peptidyl-lysine oxidation, Regulation of heart rate by chemical signal, and Keratinocyte development. Each is linked with GNG11 in more than 10 cancer types. Because this analysis shows association rather than direction, both GNG11-to-partner and partner-to-GNG11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine oxidation grouped by GNG11-low versus GNG11-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GNG11→partner) and Y-score (partner→GNG11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Peptidyl-lysine oxidation →	+1.416	+2.917	<.001	.003	2	11
SOFT_TISSUE	Regulation of heart rate by chemical signal →	+0.288	+3.288	<.001	<.001	3	9
URINARY_TRACT	Keratinocyte development →	+0.436	+2.722	<.001	.001	3	9
SKIN	Vesicle cargo loading →	+0.088	+1.647	.005	.005	3	9
SKIN	Positive regulation of insulin-like growth factor receptor signaling pathway →	-0.919	-2.068	.002	<.001	3	9
LIVER	Positive regulation of nitric-oxide synthase activity →	-1.299	-2.408	.007	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,212 associations by consensus.

Peptidyl-lysine oxidation by GNG11 expression — STOMACH

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