Across TCGA patient cohorts, GNB1L RNA expression is significantly associated with the protein abundance of many other proteins, with 12,794 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GNB1L-associated proteins across cancer lineages are SEPSECS, CCDC28A, and NUMB. Each is linked with GNB1L in more than 4 cancer types. Because this analysis shows association rather than direction, both GNB1L-to-partner and partner-to-GNB1L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNB1L→partner) and Y-score (partner→GNB1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SEPSECS →	-0.319	-0.197	<.001	<.001	3	5
GBM	CCDC28A →	-0.279	-0.290	.004	.003	3	5
CCRCC	NUMB →	-0.228	-0.203	.001	.002	3	5
CCRCC	ARHGEF37 →	-0.494	-0.215	<.001	.001	3	4
GBM	ARID2 →	+0.340	+0.443	<.001	<.001	3	4
OV	RANBP1 →	+0.359	+0.419	.009	.005	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,794 associations by consensus.

Exploration

GNB1L survival (RNA) · tumor vs normal (RNA) · all GNB1L data types