GNAI2

Across TCGA patient cohorts, GNAI2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,282 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GNAI2-associated proteins across cancer lineages are CNN2, PLAU, and POLDIP2. Each is linked with GNAI2 in more than 8 cancer types. Because this analysis shows association rather than direction, both GNAI2-to-partner and partner-to-GNAI2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNAI2 versus CNN2 in GBM, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNAI2→partner) and Y-score (partner→GNAI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CNN2 →	+0.787	+0.309	<.001	<.001	3	9
GBM	PLAU →	+0.812	+0.323	<.001	<.001	3	7
CCRCC	POLDIP2 →	-0.291	-0.443	<.001	<.001	3	7
GBM	PPP1R18 →	+0.462	+0.367	<.001	<.001	3	7
PDAC	ITGA5 →	+0.519	+0.287	<.001	<.001	3	7
OV	TFB2M →	-0.524	-0.470	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,282 associations by consensus.

GNAI2 vs CNN2 — GBM

Explore this scatter interactively →