GNAI2

Across TCGA patient cohorts, GNAI2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,889 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GNAI2-associated genes across cancer lineages are PILRA, CYTH4, and NCF4. Each is linked with GNAI2 in more than 8 cancer types. Because this analysis shows association rather than direction, both GNAI2-to-partner and partner-to-GNAI2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNAI2 versus PILRA in HNSC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNAI2→partner) and Y-score (partner→GNAI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PILRA →	+1.044	+0.320	<.001	<.001	3	9
GBM	CYTH4 →	+0.952	+0.325	<.001	<.001	3	8
HNSC	NCF4 →	+1.153	+0.275	<.001	<.001	3	8
HNSC	TLR8 →	+1.420	+0.378	<.001	<.001	3	8
GBM	CD37 →	+0.754	+0.333	<.001	<.001	3	8
GBM	LILRB1 →	+0.936	+0.380	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,889 associations by consensus.

GNAI2 vs PILRA — HNSC

Explore this scatter interactively →