GNA14

Across TCGA pan-cancer cohorts, GNA14 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated GNA14 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher GNA14 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated GNA14 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

LUAD, PDAC, and CCRCC are the cancer types where GNA14 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	III,IV	0.861	0.273	<.001	18	view →
PDAC	DFS	Median	All	0.279	0.695	.038	10	view →
CCRCC	DFS	Median	III,IV	0.264	0.791	.036	5	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

GNA14–LUAD (OS)

Open the LUAD breakdown →