GNA14

Across TCGA cell cohorts, GNA14 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,425 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GNA14-associated GO terms across cancer lineages are Phospholipase C-activating dopamine receptor signaling pathway, Negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with GNA14 in more than 8 cancer types. Because this analysis shows association rather than direction, both GNA14-to-partner and partner-to-GNA14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phospholipase C-activating dopamine receptor signaling pathway grouped by GNA14-low versus GNA14-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GNA14→partner) and Y-score (partner→GNA14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Phospholipase C-activating dopamine receptor signaling pathway →	-0.403	-0.733	.007	.003	2	9
BREAST	Negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.090	+0.776	<.001	.006	3	7
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.142	+0.227	<.001	.001	3	7
LUNG_SCLC	Golgi vesicle transport →	+0.063	+1.180	<.001	<.001	3	7
LIVER	Fertilization →	-0.073	-0.076	.002	.009	3	6
LARGE_INTESTINE	Carbohydrate homeostasis →	+0.041	+0.670	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,425 associations by consensus.

Phospholipase C-activating dopamine receptor signaling pathway by GNA14 expression — PANCREAS

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