GNA14

Across TCGA cell cohorts, GNA14 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible GNA14-associated genes across cancer lineages are LILRA1, PROP1, and PRAMEF20. Each is linked with GNA14 in more than 1 cancer types. Because this analysis shows association rather than direction, both GNA14-to-partner and partner-to-GNA14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LILRA1 grouped by GNA14-low versus GNA14-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNA14→partner) and Y-score (partner→GNA14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	LILRA1 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	PROP1 →	+0.030	+4.906	<.001	.006	3	1
OESOPHAGUS	PRAMEF20 →	+0.013	+4.906	<.001	.006	3	1
OESOPHAGUS	GAGE12H →	+0.053	+4.906	<.001	.006	3	1
LARGE_INTESTINE	LHCGR →	+0.050	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

LILRA1 by GNA14 expression — OESOPHAGUS

Explore this box plot interactively →