GNA14-AS1

Across TCGA pan-cancer cohorts, GNA14-AS1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated GNA14-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher GNA14-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated GNA14-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and LUAD show a favorable association.

KIRC, THYM, and KICH are the cancer types where GNA14-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Quartile	II,III,IV	0.562	0.766	<.001	87	view →
THYM	DFS	Tertile	All	0.698	0.917	<.001	63	view →
KICH	DFS	Tertile	II,III,IV	0.446	0.855	.002	51	view →
BRCA	OS	Median	II,III,IV	0.944	0.888	.001	50	view →
UVM	OS	Tertile	All	0.276	0.618	.006	36	view →
MESO	DFS	Tertile	IV	0.135	0.411	.002	27	view →
LAML	DFS	Tertile	All	0.479	0.685	.015	18	view →
SKCM	DFS	Tertile	IV	0.055	0.572	.002	13	view →
LUAD	OS	Median	All	0.413	0.298	.010	8	view →
LIHC	OS	Tertile	II,III,IV	0.237	0.525	.009	6	view →
ESCA	OS	Tertile	III,IV	0.531	0.295	.048	2	view →
SARC	DFS	Median	All	0.506	0.311	.036	2	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

GNA14-AS1–KIRC (OS)

Open the KIRC breakdown →