GNA14-AS1

Across TCGA pan-cancer cohorts, GNA14-AS1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of GNA14-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where GNA14-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types GNA14-AS1 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

THCA, LUSC, and KICH are the cancer types where GNA14-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GNA14-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.178	<.001	7	view →
LUSC	Male	II,III,IV	−0.402	<.001	6	view →
KICH	All	All	−0.075	.003	3	view →
KIRP	All	All	−0.116	.002	2	view →
KIRC	Female	IV	−0.156	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

GNA14-AS1–THCA

Open the THCA breakdown →