GNA12

Across TCGA patient cohorts, GNA12 protein abundance is significantly associated with the RNA expression of many other genes, with 10,651 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GNA12-associated genes across cancer lineages are FKBP14, PRICKLE2, and ZCCHC24. Each is linked with GNA12 in more than 5 cancer types. Because this analysis shows association rather than direction, both GNA12-to-partner and partner-to-GNA12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNA12 versus FKBP14 in COAD, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNA12→partner) and Y-score (partner→GNA12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FKBP14 →	+0.705	+0.280	.002	.008	3	6
UCEC	PRICKLE2 →	+0.783	+0.339	<.001	<.001	3	5
UCEC	ZCCHC24 →	+0.763	+0.286	<.001	.001	3	5
UCEC	PDGFA →	+0.920	+0.292	.003	.004	3	5
GBM	PLPPR4 →	+1.022	+0.352	.002	.001	3	4
OV	CNRIP1 →	+0.707	+0.223	<.001	.005	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,651 associations by consensus.

GNA12 vs FKBP14 — COAD

Explore this scatter interactively →