GNA11

Across TCGA patient cohorts, GNA11 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,445 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GNA11-associated proteins across cancer lineages are THOP1, PTPRC, and SGTA. Each is linked with GNA11 in more than 5 cancer types. Because this analysis shows association rather than direction, both GNA11-to-partner and partner-to-GNA11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNA11 versus THOP1 in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNA11→partner) and Y-score (partner→GNA11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	THOP1 →	+0.279	+0.471	<.001	<.001	3	6
UCEC	PTPRC →	-0.622	-0.460	.005	.001	3	6
LSCC	SGTA →	+0.348	+0.701	<.001	<.001	3	5
LSCC	THEMIS2 →	-0.474	-0.483	<.001	<.001	3	5
LSCC	ADA2 →	-0.548	-0.515	<.001	<.001	3	5
LSCC	SAMSN1 →	-0.554	-0.665	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,445 associations by consensus.

GNA11 vs THOP1 — OV

Explore this scatter interactively →