GMPS

Across TCGA cell cohorts, GMPS RNA expression is significantly associated with the go_rna of many other GO terms, with 3,410 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GMPS-associated GO terms across cancer lineages are Positive regulation of cell cycle, Regulation of G2/M transition of mitotic cell cycle, and Mitotic nuclear division. Each is linked with GMPS in more than 15 cancer types. Because this analysis shows association rather than direction, both GMPS-to-partner and partner-to-GMPS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell cycle grouped by GMPS-low versus GMPS-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GMPS→partner) and Y-score (partner→GMPS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of cell cycle →	+0.061	+0.949	<.001	.003	3	16
URINARY_TRACT	Regulation of G2/M transition of mitotic cell cycle →	+0.079	+0.750	.002	.004	3	15
SOFT_TISSUE	Mitotic nuclear division →	+0.087	+0.650	.002	.001	3	15
URINARY_TRACT	Positive regulation of chromosome separation →	+0.169	+0.860	.002	.001	3	15
SKIN	Protein localization to kinetochore →	+0.147	+0.604	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Interstrand cross-link repair →	+0.074	+0.796	<.001	.002	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,410 associations by consensus.

Positive regulation of cell cycle by GMPS expression — KIDNEY

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