GML

Across TCGA patient cohorts, GML protein abundance is significantly associated with the protein abundance of many other proteins, with 11,560 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GML-associated proteins across cancer lineages are SACS_S2511, SACS_S4264, and PDLIM3. Each is linked with GML in more than 4 cancer types. Because this analysis shows association rather than direction, both GML-to-partner and partner-to-GML results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GML versus SACS_S2511 in HNSC, with a Pearson correlation of 0.50.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GML→partner) and Y-score (partner→GML) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SACS_S2511 →	+0.874	+0.511	<.001	<.001	3	5
GBM	SACS_S4264 →	+0.532	+0.419	<.001	<.001	3	5
HNSC	PDLIM3 →	+1.205	+0.347	<.001	<.001	3	4
BRCA	PLOD1 →	+0.455	+0.389	<.001	<.001	3	4
PDAC	TJP3_S164 →	-0.959	-0.574	<.001	<.001	3	4
CCRCC	CTHRC1 →	+0.903	+0.572	.002	.002	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,560 associations by consensus.

GML vs SACS_S2511 — HNSC

Explore this scatter interactively →