GM2AP2

Across TCGA pan-cancer cohorts, GM2AP2 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated GM2AP2 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher GM2AP2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GM2AP2 expression acts as an unfavorable survival marker, although some lineages such as ESCA and HNSC show a favorable association.

KIRC, KICH, and PAAD are the cancer types where GM2AP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.521	0.683	<.001	87	view →
KICH	OS	Tertile	II,III,IV	0.070	0.828	<.001	54	view →
PAAD	OS	Tertile	All	0.238	0.504	.014	36	view →
ESCA	OS	Tertile	III,IV	0.757	0.329	.001	35	view →
UCS	DFS	Median	IV	0.304	0.897	.001	24	view →
TGCT	DFS	Tertile	All	0.695	0.850	.019	18	view →
LAML	DFS	Tertile	All	0.387	0.623	.022	18	view →
KIRP	OS	Tertile	IV	0.042	0.470	.047	9	view →
READ	OS	Tertile	IV	0.557	0.883	.040	9	view →
GBM	DFS	Tertile	All	0.144	0.265	.041	9	view →
HNSC	OS	Tertile	All	0.851	0.735	.018	9	view →
LIHC	OS	Tertile	II,III,IV	1.000	0.708	.015	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

GM2AP2–KIRC (DFS)

Open the KIRC breakdown →