Across TCGA patient cohorts, GLYATL3 mutation is significantly associated with the RNA expression of many other genes, with 1,456 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLYATL3-associated genes across cancer lineages are MIR588, TRAJ22, and IGHV3OR16-13. Each is linked with GLYATL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLYATL3-to-partner and partner-to-GLYATL3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLYATL3→partner) and Y-score (partner→GLYATL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR588 →	+0.373	+5.003	<.001	.004	3	2
COAD	TRAJ22 →	+1.175	+4.181	<.001	.009	3	2
UCEC	IGHV3OR16-13 →	+0.717	+2.167	<.001	.003	3	1
UCEC	IGKV2OR2-2 →	+0.097	+2.496	.009	.003	3	1
UCEC	CCL5 →	+1.452	+3.475	<.001	.002	3	1
UCEC	IGKV1OR2-6 →	+1.061	+1.967	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,456 associations by consensus.

Exploration

GLYATL3 survival (RNA) · tumor vs normal (RNA) · all GLYATL3 data types