GLUD2

Across TCGA patient cohorts, GLUD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,221 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GLUD2-associated proteins across cancer lineages are PLEKHA6, HECTD1, and SLK. Each is linked with GLUD2 in more than 3 cancer types. Because this analysis shows association rather than direction, both GLUD2-to-partner and partner-to-GLUD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GLUD2 versus PLEKHA6 in GBM, with a Pearson correlation of 0.20.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GLUD2→partner) and Y-score (partner→GLUD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLEKHA6 →	+0.443	+0.755	<.001	.004	3	4
HNSC	HECTD1 →	-0.175	-0.518	.005	.003	3	3
GBM	SLK →	+0.208	+0.698	<.001	<.001	3	3
GBM	DIP2C →	+0.497	+0.952	<.001	<.001	3	3
GBM	AKR1C3 →	+1.050	+0.936	<.001	<.001	3	3
LSCC	PLEKHA6_S459 →	+0.847	+0.499	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,221 associations by consensus.

GLUD2 vs PLEKHA6 — GBM

Explore this scatter interactively →