GLUD2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GLUD2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,259 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GLUD2-associated genes across cancer lineages are PDGFRA, MAP3K4-AS1, and ZNF781. Each is linked with GLUD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both GLUD2-to-partner and partner-to-GLUD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GLUD2 versus PDGFRA in OV, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLUD2→partner) and Y-score (partner→GLUD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVPDGFRA →-1.033-0.421.003.00633
OVMAP3K4-AS1 →-0.605-0.556<.001<.00133
BRCAZNF781 →-0.343-0.525.002.00233
LUADFUT11 →-0.353-0.908.003<.00133
CCRCCTTC23 →-0.285-0.227.001.00232
OVP3H3 →-1.441-0.502<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,259 associations by consensus.

GLUD2 vs PDGFRA — OV

Per-sample scatter of GLUD2 vs PDGFRA in OV (Pearson r = -0.34).

Explore this scatter interactively →

Exploration