GLUD1

Across TCGA cell cohorts, GLUD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,901 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GLUD1-associated GO terms across cancer lineages are Ornithine metabolic process, Guanine nucleotide transport, and Guanine nucleotide transmembrane transport. Each is linked with GLUD1 in more than 11 cancer types. Because this analysis shows association rather than direction, both GLUD1-to-partner and partner-to-GLUD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ornithine metabolic process grouped by GLUD1-low versus GLUD1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GLUD1→partner) and Y-score (partner→GLUD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Ornithine metabolic process →	+0.109	+0.785	.003	<.001	3	12
LUNG_SCLC	Guanine nucleotide transport →	+0.074	+0.505	.007	.005	3	7
LUNG_SCLC	Guanine nucleotide transmembrane transport →	+0.098	+0.539	.003	.003	3	7
SKIN	Allantoin metabolic process →	+0.118	+0.469	<.001	<.001	3	7
PANCREAS	Phosphatidylinositol metabolic process →	+0.032	+0.554	.002	.001	3	7
LUNG_SCLC	GMP biosynthetic process →	+0.128	+0.617	.002	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,901 associations by consensus.

Ornithine metabolic process by GLUD1 expression — LUNG_SCLC

Explore this box plot interactively →