GLT8D2

Across TCGA cell cohorts, GLT8D2 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GLT8D2-associated genes across cancer lineages are OR7E24, PRAMEF18, and TMCO5A. Each is linked with GLT8D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLT8D2-to-partner and partner-to-GLT8D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7E24 grouped by GLT8D2-low versus GLT8D2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLT8D2→partner) and Y-score (partner→GLT8D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR7E24 →	+0.006	+6.266	<.001	<.001	3	1
LUNG_NSCLC_LUAD	PRAMEF18 →	+0.006	+4.887	<.001	.009	3	1
LARGE_INTESTINE	TMCO5A →	+0.019	+4.415	<.001	.007	3	1
SKIN	AHSP →	+0.045	+3.240	<.001	.004	3	1
SKIN	PIWIL3 →	+0.022	+2.933	<.001	.003	3	1
LARGE_INTESTINE	ACSM6 →	+0.032	+4.169	<.001	.007	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

OR7E24 by GLT8D2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →