GLT1D1

Across TCGA patient cohorts, GLT1D1 mutation is significantly associated with the RNA expression of many other genes, with 1,071 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLT1D1-associated genes across cancer lineages are RNU6-290P, F8A2, and OPALIN. Each is linked with GLT1D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLT1D1-to-partner and partner-to-GLT1D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-290P grouped by GLT1D1-low versus GLT1D1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLT1D1→partner) and Y-score (partner→GLT1D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-290P →	+0.357	+7.731	<.001	.009	3	2
UCEC	F8A2 →	+0.029	+3.209	<.001	<.001	3	2
LUAD	OPALIN →	+0.030	+4.399	<.001	.006	3	2
COAD	RPS15AP32 →	+0.396	+6.392	<.001	.001	3	2
UCEC	PSMD9 →	+0.382	+2.415	.005	.003	3	2
UCEC	PSPN →	+0.542	+3.119	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,071 associations by consensus.

RNU6-290P by GLT1D1 expression — BRCA

Explore this box plot interactively →