GLT1D1

Across TCGA pan-cancer cohorts, GLT1D1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated GLT1D1 data layer compared with 4 for mutation status.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher GLT1D1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated GLT1D1 expression acts as an unfavorable survival marker, although some lineages such as UVM and THCA show a favorable association.

STAD, UVM, and THCA are the cancer types where GLT1D1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Tertile	III,IV	0.281	0.680	<.001	65	view →
UVM	OS	Median	III,IV	0.872	0.492	.002	55	view →
THCA	OS	Tertile	II,III,IV	1.000	0.808	.002	47	view →
HNSC	DFS	Quartile	IV	0.495	0.165	<.001	39	view →
ESCA	DFS	Tertile	III,IV	0.497	0.218	.004	34	view →
KIRC	DFS	Median	All	0.580	0.694	.008	24	view →
THYM	OS	Median	II,III,IV	0.692	1.000	.010	22	view →
MESO	OS	Median	All	0.481	0.299	.005	19	view →
SKCM	DFS	Median	IV	0.763	0.187	.006	15	view →
ACC	DFS	Median	III,IV	0.276	0.749	.003	13	view →
UCS	DFS	Tertile	IV	0.459	0.938	.024	12	view →
COAD	OS	Median	III,IV	0.576	0.780	.016	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

GLT1D1–STAD (OS)

Open the STAD breakdown →