GLT1D1

Across TCGA cell cohorts, GLT1D1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GLT1D1-associated genes across cancer lineages are ART1, NPHS2, and SPINK9. Each is linked with GLT1D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLT1D1-to-partner and partner-to-GLT1D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ART1 grouped by GLT1D1-low versus GLT1D1-high in LIVER.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLT1D1→partner) and Y-score (partner→GLT1D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	ART1 →	+0.142	+3.977	.008	.006	3	1
SKIN	NPHS2 →	+0.023	+5.415	<.001	.004	3	1
SKIN	SPINK9 →	+0.058	+5.415	<.001	.004	3	1
LUNG_SCLC	OPRPN →	+0.139	+5.029	<.001	.006	3	1
LUNG_SCLC	OR9I1 →	+0.023	+5.643	<.001	.002	3	1
LUNG_SCLC	OR2L8 →	+0.155	+5.029	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

ART1 by GLT1D1 expression — LIVER

Explore this box plot interactively →