GLRXP3

Across TCGA patient cohorts, GLRXP3 mutation is significantly associated with the RNA expression of many other genes, with 49 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible GLRXP3-associated genes across cancer lineages are MIR6854, RNA5SP414, and RNA5SP411. Each is linked with GLRXP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLRXP3-to-partner and partner-to-GLRXP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6854 grouped by GLRXP3-low versus GLRXP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLRXP3→partner) and Y-score (partner→GLRXP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6854 →	+0.373	+4.582	<.001	.005	3	2
UCEC	RNA5SP414 →	+1.126	+4.255	<.001	<.001	3	1
UCEC	RNA5SP411 →	+2.691	+4.715	<.001	<.001	3	1
UCEC	RNA5SP412 →	+0.954	+3.967	<.001	.001	3	1
SKCM	FXYD6P3 →	+0.096	+4.624	<.001	.005	3	1
SKCM	ANKRD36P1 →	+0.530	+3.449	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

MIR6854 by GLRXP3 expression — UCEC

Explore this box plot interactively →