GLRXP3

Across TCGA pan-cancer cohorts, GLRXP3 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of GLRXP3’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where GLRXP3 RNA is repressed in tumor relative to normal tissue. In most cancer types GLRXP3 is over-expressed in tumor, although a few such as LUSC and PAAD show the opposite, repressed pattern.

LUSC, KIRC, and PAAD are the cancer types where GLRXP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GLRXP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.254	.002	5	view →
KIRC	All	II,III,IV	+0.354	.017	4	view →
PAAD	Female	All	−0.760	.024	2	view →
PRAD	All	All	−0.135	.033	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

GLRXP3–LUSC

Open the LUSC breakdown →