Q-omics provides the consensus-scored GLRX5P3 profile across patient tissues and cancer cell-line models. GLRX5P3 expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, GLRX5P3 is differentially expressed in 4, with the highest sampling consensus in KIRP. Additionally, GLRX5P3 RNA expression shows 13,680 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight KIRC, KIRP, and UVM as cancer lineages where GLRX5P3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for GLRX5P3 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes GLRX5P3 survival associations across molecular data types. GLRX5P3 RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible GLRX5P3 RNA expression–survival associations across cancer types. High GLRX5P3 expression shows unfavorable associations in KIRC, PRAD, ACC and DLBC, but favorable associations in UCS and KIRP. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for GLRX5P3 RNA expression.
This table summarizes GLRX5P3 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in KIRP for RNA.
This table ranks reproducible tumor–normal expression differences for GLRX5P3. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. GLRX5P3 shows higher tumor expression in KIRP, KIRC, UCEC and HNSC. The KIRP box plot shows higher GLRX5P3 RNA expression in tumor versus normal tissue (log2 FC = +0.453, t-test p = .013).
This table shows molecular features associated with GLRX5P3 in patient tissues and cancer cell lines. In patient samples, GLRX5P3 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set. In cancer cell lines, GLRX5P3 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in NCI60_ALL.
