GLRB

Across TCGA patient cohorts, GLRB mutation is significantly associated with the RNA expression of many other genes, with 2,098 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLRB-associated genes across cancer lineages are MYL12BP1, SULT6B1, and RCC2P3. Each is linked with GLRB in more than 2 cancer types. Because this analysis shows association rather than direction, both GLRB-to-partner and partner-to-GLRB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYL12BP1 grouped by GLRB-low versus GLRB-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLRB→partner) and Y-score (partner→GLRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MYL12BP1 →	+0.224	+1.517	.003	.001	3	3
READ	SULT6B1 →	+0.062	+4.827	<.001	.002	3	2
READ	RCC2P3 →	+0.064	+4.626	<.001	.004	3	2
READ	KRT90P →	+0.108	+5.257	<.001	.002	3	2
BLCA	RNU6-728P →	+0.640	+5.106	<.001	.008	3	2
UCEC	COX15 →	+0.499	+2.708	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,098 associations by consensus.

MYL12BP1 by GLRB expression — SKCM

Explore this box plot interactively →