GLRB

Across TCGA cell cohorts, GLRB RNA expression is significantly associated with the go_rna of many other GO terms, with 3,895 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GLRB-associated GO terms across cancer lineages are Synaptic transmission, glycinergic, Golgi vesicle transport, and Regulation of focal adhesion assembly. Each is linked with GLRB in more than 19 cancer types. Because this analysis shows association rather than direction, both GLRB-to-partner and partner-to-GLRB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Synaptic transmission, glycinergic grouped by GLRB-low versus GLRB-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GLRB→partner) and Y-score (partner→GLRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Synaptic transmission, glycinergic →	+1.963	+2.058	<.001	<.001	3	20
CNS	Golgi vesicle transport →	+0.047	+1.357	<.001	<.001	3	10
BONE	Regulation of focal adhesion assembly →	+0.119	+0.963	.001	.003	3	9
BONE	Regulation of cell-substrate junction assembly →	+0.119	+0.963	.001	.003	3	9
BONE	Viral life cycle →	+0.081	+1.285	.001	<.001	3	9
SKIN	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.055	+1.072	<.001	.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,895 associations by consensus.

Synaptic transmission, glycinergic by GLRB expression — LUNG_NSCLC_LUSC

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