GLRB

Across TCGA cell cohorts, GLRB mutation is significantly associated with the RNA expression of many other genes, with 136 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GLRB-associated genes across cancer lineages are OR6C2, GGTLC2, and MOGAT1. Each is linked with GLRB in more than 1 cancer types. Because this analysis shows association rather than direction, both GLRB-to-partner and partner-to-GLRB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6C2 grouped by GLRB-low versus GLRB-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLRB→partner) and Y-score (partner→GLRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR6C2 →	+0.066	+4.409	<.001	.005	3	1
SKIN	GGTLC2 →	+0.024	+2.688	<.001	.008	3	1
SKIN	MOGAT1 →	+0.093	+3.577	<.001	.002	3	1
SKIN	MINAR2 →	+0.007	+3.977	<.001	<.001	3	1
LARGE_INTESTINE	GCAT →	+1.216	+3.321	.001	.003	3	1
LARGE_INTESTINE	FAH →	-0.958	-3.541	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 136 associations by consensus.

OR6C2 by GLRB expression — BLOOD_Leukemia

Explore this box plot interactively →