GLRA2

Across TCGA patient cohorts, GLRA2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,729 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GLRA2-associated genes across cancer lineages are CHGA, PROKR2, and HTR2A. Each is linked with GLRA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLRA2-to-partner and partner-to-GLRA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GLRA2 versus CHGA in GBM, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLRA2→partner) and Y-score (partner→GLRA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CHGA →	+2.726	+0.857	<.001	.001	3	1
GBM	PROKR2 →	+0.495	+0.584	<.001	.001	3	1
GBM	HTR2A →	+1.623	+0.608	<.001	.009	3	1
GBM	SLC17A7 →	+2.611	+0.792	<.001	.003	3	1
GBM	RAB3A →	+1.810	+0.865	.002	.002	3	1
GBM	EPHB6 →	+2.194	+0.747	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,729 associations by consensus.

GLRA2 vs CHGA — GBM

Explore this scatter interactively →