GLRA2

Across TCGA patient cohorts, GLRA2 mutation is significantly associated with the RNA expression of many other genes, with 5,716 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLRA2-associated genes across cancer lineages are ADNP2, OIP5, and RAI1. Each is linked with GLRA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both GLRA2-to-partner and partner-to-GLRA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADNP2 grouped by GLRA2-low versus GLRA2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLRA2→partner) and Y-score (partner→GLRA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ADNP2 →	+0.769	+1.975	<.001	<.001	3	3
UCEC	OIP5 →	+0.940	+2.786	<.001	<.001	3	3
UCEC	RAI1 →	+0.518	+1.546	<.001	.001	3	3
UCEC	FANCE →	+0.405	+2.828	.004	.001	3	3
UCEC	SLC25A51 →	+0.359	+2.212	<.001	.001	3	3
UCEC	HNRNPR →	+0.645	+1.986	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,716 associations by consensus.

ADNP2 by GLRA2 expression — UCEC

Explore this box plot interactively →