GLP2R

Across TCGA patient cohorts, GLP2R mutation is significantly associated with the RNA expression of many other genes, with 2,072 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLP2R-associated genes across cancer lineages are C1orf109, MED8, and EOLA1. Each is linked with GLP2R in more than 2 cancer types. Because this analysis shows association rather than direction, both GLP2R-to-partner and partner-to-GLP2R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1orf109 grouped by GLP2R-low versus GLP2R-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLP2R→partner) and Y-score (partner→GLP2R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	C1orf109 →	+0.434	+2.712	.007	.003	3	3
UCEC	MED8 →	+0.282	+2.346	.006	.003	3	3
SKCM	EOLA1 →	+0.340	+2.398	<.001	<.001	3	3
UCEC	MRPL37 →	+0.370	+2.135	.009	.002	3	3
READ	MTCO1P39 →	+0.219	+4.925	<.001	.004	3	2
READ	CDK4P1 →	+0.119	+4.421	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,072 associations by consensus.

C1orf109 by GLP2R expression — LUSC

Explore this box plot interactively →