GLP2R

Across TCGA pan-cancer cohorts, GLP2R RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of GLP2R’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where GLP2R RNA is repressed in tumor relative to normal tissue. In most cancer types GLP2R is over-expressed in tumor, although a few such as COAD and BLCA show the opposite, repressed pattern.

COAD, BLCA, and READ are the cancer types where GLP2R tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GLP2R RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	III,IV	−2.306	<.001	12	view →
BLCA	Male	IV	−4.392	<.001	11	view →
READ	All	II,III,IV	−2.632	<.001	7	view →
THCA	Male	All	−0.290	<.001	7	view →
BRCA	All	III,IV	−1.081	<.001	6	view →
STAD	All	All	−0.900	<.001	6	view →
UCEC	All	III,IV	−0.632	<.001	6	view →
LIHC	Male	III,IV	−0.447	<.001	6	view →
LUSC	Female	All	−0.650	<.001	5	view →
KICH	All	All	−0.632	<.001	5	view →
LUAD	All	All	−0.339	<.001	5	view →
PRAD	All	All	−0.084	.047	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

GLP2R–COAD

Open the COAD breakdown →