GLP2R

Across TCGA patient cohorts, GLP2R mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLP2R-associated genes across cancer lineages are Cyclin-B1, PDCD4, and Caspase-7-cleavedD198. Each is linked with GLP2R in more than 2 cancer types. Because this analysis shows association rather than direction, both GLP2R-to-partner and partner-to-GLP2R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by GLP2R-low versus GLP2R-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLP2R→partner) and Y-score (partner→GLP2R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.446	+1.415	.034	.046	3	3
UCEC	PDCD4 →	-0.388	-2.999	.028	.035	3	3
UCEC	Caspase-7-cleavedD198 →	+0.621	+2.479	.005	.010	3	3
UCEC	p38-MAPK_pT180_Y182 →	-0.368	-2.000	.029	.030	3	2
UCEC	ERK2 →	+0.143	+1.415	.047	.046	3	2
UCEC	Src_pY527 →	-0.466	-3.321	.003	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Cyclin-B1 by GLP2R expression — UCEC

Explore this box plot interactively →