GLP2R

Across TCGA cell cohorts, GLP2R RNA expression is significantly associated with the go_rna of many other GO terms, with 1,651 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible GLP2R-associated GO terms across cancer lineages are Substrate adhesion-dependent cell spreading, Regulation of intracellular transport, and Renal filtration cell differentiation. Each is linked with GLP2R in more than 8 cancer types. Because this analysis shows association rather than direction, both GLP2R-to-partner and partner-to-GLP2R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Substrate adhesion-dependent cell spreading grouped by GLP2R-low versus GLP2R-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GLP2R→partner) and Y-score (partner→GLP2R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Substrate adhesion-dependent cell spreading →	+0.192	+0.926	.001	<.001	3	9
BREAST	Regulation of intracellular transport →	+0.048	+0.740	<.001	.004	3	8
KIDNEY	Renal filtration cell differentiation →	+0.255	+0.591	<.001	.006	3	8
KIDNEY	Podocyte differentiation →	+0.255	+0.591	<.001	.006	3	8
KIDNEY	Glomerular epithelial cell differentiation →	+0.261	+0.665	<.001	.005	3	8
SKIN	Endodermal cell differentiation →	+0.155	+0.159	<.001	.003	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,651 associations by consensus.

Substrate adhesion-dependent cell spreading by GLP2R expression — LUNG_NSCLC_LUSC

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