GLP2R

Across TCGA cell cohorts, GLP2R mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible GLP2R-associated genes across cancer lineages are OR2B3, OR8B12, and OR8A1. Each is linked with GLP2R in more than 1 cancer types. Because this analysis shows association rather than direction, both GLP2R-to-partner and partner-to-GLP2R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2B3 grouped by GLP2R-low versus GLP2R-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLP2R→partner) and Y-score (partner→GLP2R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR2B3 →	+0.017	+4.643	<.001	.004	3	1
LUNG_NSCLC_LUAD	OR8B12 →	+0.041	+3.564	<.001	.001	3	1
LUNG_NSCLC_LUAD	OR8A1 →	+0.218	+3.043	.004	.006	3	1
LUNG_NSCLC_LUAD	OR8G1 →	+0.050	+2.896	.009	.008	3	1
LUNG_NSCLC_LUAD	OR8G5 →	+0.382	+2.882	.004	.009	3	1
LUNG_NSCLC_LUAD	CD209 →	+0.011	+2.896	.003	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

OR2B3 by GLP2R expression — LUNG_SCLC

Explore this box plot interactively →