GLP1R

Across TCGA pan-cancer cohorts, GLP1R mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated GLP1R data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GLP1R mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated GLP1R expression acts as an unfavorable survival marker, although some lineages such as HNSC and CCRCC show a favorable association.

UCEC, HNSC, and LUAD are the cancer types where GLP1R mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	III,IV	0.458	1.000	.010	28	view →
HNSC	OS	Quartile	II,III,IV	1.000	0.506	.002	19	view →
LUAD	OS	Median	All	0.529	0.832	.002	18	view →
CCRCC	OS	Median	III,IV	1.000	0.805	.014	16	view →
LSCC	OS	Tertile	All	0.725	0.940	.010	13	view →
GBM	DFS	Quartile	All	0.454	0.197	.031	4	view →
PDAC	DFS	Median	IV	0.228	0.763	.047	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

GLP1R–UCEC (DFS)

Open the UCEC breakdown →