GLP1R

Across TCGA pan-cancer cohorts, GLP1R RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of GLP1R’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where GLP1R RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GLP1R is over-expressed in tumor, although a few such as LUSC and KICH show the opposite, repressed pattern.

UCEC, LUSC, and KICH are the cancer types where GLP1R tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GLP1R RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	+0.528	.002	6	view →
LUSC	All	II,III,IV	−0.325	.001	6	view →
KICH	All	All	−0.127	<.001	6	view →
LIHC	All	All	+0.243	.003	5	view →
BRCA	Female	All	−0.581	<.001	4	view →
LUAD	Male	II,III,IV	−0.348	.001	3	view →
THCA	All	All	+0.422	.021	2	view →
KIRC	Female	All	+0.409	.006	2	view →
STAD	Female	III,IV	−0.890	.032	1	view →
BLCA	All	III,IV	+0.392	.047	1	view →
KIRP	All	All	+0.346	.014	1	view →
CHOL	Male	All	+0.126	.025	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

GLP1R–UCEC

Open the UCEC breakdown →