GLP1R

Across TCGA patient cohorts, GLP1R mutation is significantly associated with the RNA expression of many other genes, with 2,671 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLP1R-associated genes across cancer lineages are MIR4717, OR4A49P, and RNU6-1138P. Each is linked with GLP1R in more than 2 cancer types. Because this analysis shows association rather than direction, both GLP1R-to-partner and partner-to-GLP1R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4717 grouped by GLP1R-low versus GLP1R-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLP1R→partner) and Y-score (partner→GLP1R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR4717 →	+0.330	+4.788	<.001	.006	3	3
LIHC	OR4A49P →	+0.076	+6.008	<.001	.002	3	3
COAD	RNU6-1138P →	+0.424	+4.790	<.001	.006	3	3
BLCA	ETF1P3 →	+0.066	+4.396	<.001	.006	3	3
LIHC	MIR596 →	+0.958	+5.355	<.001	.005	3	2
BLCA	OR4A1P →	+0.037	+5.618	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,671 associations by consensus.

MIR4717 by GLP1R expression — BLCA

Explore this box plot interactively →