GLP1R

Across TCGA cell cohorts, GLP1R RNA expression is significantly associated with the go_rna of many other GO terms, with 371 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible GLP1R-associated GO terms across cancer lineages are Purine nucleoside triphosphate metabolic process, Negative regulation of ubiquitin-dependent protein catabolic process, and Nucleoside triphosphate metabolic process. Each is linked with GLP1R in more than 5 cancer types. Because this analysis shows association rather than direction, both GLP1R-to-partner and partner-to-GLP1R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine nucleoside triphosphate metabolic process grouped by GLP1R-low versus GLP1R-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GLP1R→partner) and Y-score (partner→GLP1R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Purine nucleoside triphosphate metabolic process →	+0.066	+0.869	.003	.004	3	5
CNS	Negative regulation of ubiquitin-dependent protein catabolic process →	+0.050	+0.010	<.001	.007	2	6
BLOOD_Leukemia	Nucleoside triphosphate metabolic process →	+0.042	+0.517	<.001	.007	3	5
LUNG_SCLC	Positive regulation of telomerase RNA localization to Cajal body →	+0.090	+0.896	.002	.009	3	4
UPPER_AERODIGESTIVE_TRACT	Protein K48-linked ubiquitination →	+0.069	+0.004	<.001	.004	3	4
OVARY	Ribonucleoside triphosphate biosynthetic process →	+0.076	+0.052	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 371 associations by consensus.

Purine nucleoside triphosphate metabolic process by GLP1R expression — LUNG_SCLC

Explore this box plot interactively →