GLO1

Across TCGA cell cohorts, GLO1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,155 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible GLO1-associated GO terms across cancer lineages are Protein peptidyl-prolyl isomerization, Centromeric sister chromatid cohesion, and DNA replication initiation. Each is linked with GLO1 in more than 16 cancer types. Because this analysis shows association rather than direction, both GLO1-to-partner and partner-to-GLO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein peptidyl-prolyl isomerization grouped by GLO1-low versus GLO1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GLO1→partner) and Y-score (partner→GLO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein peptidyl-prolyl isomerization →	+0.171	+1.313	<.001	<.001	3	17
OESOPHAGUS	Centromeric sister chromatid cohesion →	+0.177	+1.314	.006	<.001	3	16
SOFT_TISSUE	DNA replication initiation →	+0.165	+0.789	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Protein localization to nuclear inner membrane →	+0.173	+0.973	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Protein localization to condensed chromosome →	+0.152	+0.984	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Protein localization to kinetochore →	+0.169	+1.240	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,155 associations by consensus.

Protein peptidyl-prolyl isomerization by GLO1 expression — PANCREAS

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