Across TCGA patient cohorts, GLMP mutation is significantly associated with the RNA expression of many other genes, with 271 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLMP-associated genes across cancer lineages are MIR3646, RNA5SP98, and MIR513B. Each is linked with GLMP in more than 1 cancer types. Because this analysis shows association rather than direction, both GLMP-to-partner and partner-to-GLMP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLMP→partner) and Y-score (partner→GLMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR3646 →	+0.605	+7.731	<.001	.009	3	2
BRCA	RNA5SP98 →	+0.427	+7.731	<.001	.009	3	2
BRCA	MIR513B →	+0.608	+8.471	<.001	.005	3	2
BRCA	MIR548H2 →	+0.587	+7.731	<.001	.009	3	2
BRCA	MTND5P22 →	+0.322	+8.055	<.001	.007	3	2
UCEC	MIR548AC →	+0.295	+2.782	.002	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 271 associations by consensus.

Exploration

GLMP survival (RNA) · tumor vs normal (RNA) · all GLMP data types