GLIS1

Across TCGA patient cohorts, GLIS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,727 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GLIS1-associated proteins across cancer lineages are COL1A1, COL3A1, and PCOLCE. Each is linked with GLIS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both GLIS1-to-partner and partner-to-GLIS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GLIS1 versus COL1A1 in LUAD, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GLIS1→partner) and Y-score (partner→GLIS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	COL1A1 →	+0.901	+0.341	<.001	<.001	3	7
LSCC	COL3A1 →	+0.785	+0.721	<.001	<.001	3	7
OV	PCOLCE →	+0.854	+0.426	<.001	.006	3	6
LSCC	PPFIBP1 →	+0.526	+0.661	<.001	<.001	3	6
BRCA	CPXM1 →	+0.686	+0.546	<.001	<.001	3	6
BRCA	TIMP2 →	+0.637	+0.376	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,727 associations by consensus.

GLIS1 vs COL1A1 — LUAD

Explore this scatter interactively →