GLG1

Across TCGA pan-cancer cohorts, GLG1 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated GLG1 data layer compared with 24 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GLG1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated GLG1 expression acts as an unfavorable survival marker.

UCEC, ESCA, and SKCM are the cancer types where GLG1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	IV	0.219	0.745	<.001	12	view →
ESCA	DFS	Median	II,III,IV	0.082	0.523	<.001	6	view →
SKCM	DFS	Median	III,IV	0.015	0.648	<.001	4	view →
CHOL	OS	Median	All	0.155	0.725	.029	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

GLG1–UCEC (DFS)

Open the UCEC breakdown →