GLG1

Across TCGA pan-cancer cohorts, GLG1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated GLG1 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher GLG1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated GLG1 expression acts as an unfavorable survival marker.

LSCC, CCRCC, and PDAC are the cancer types where GLG1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	All	0.810	0.959	.001	37	view →
CCRCC	OS	Median	All	0.605	1.000	.001	29	view →
PDAC	DFS	Tertile	IV	0.205	0.741	.024	3	view →
LUAD	DFS	Tertile	All	0.852	1.000	.030	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

GLG1–LSCC (OS)

Open the LSCC breakdown →