GLG1

Across TCGA patient cohorts, GLG1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,239 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GLG1-associated genes across cancer lineages are ITFG1, MBTPS1, and KDELR3. Each is linked with GLG1 in more than 5 cancer types. Because this analysis shows association rather than direction, both GLG1-to-partner and partner-to-GLG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GLG1 versus ITFG1 in OV, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLG1→partner) and Y-score (partner→GLG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ITFG1 →	+0.563	+0.334	.005	.003	3	6
OV	MBTPS1 →	+0.459	+0.305	<.001	<.001	3	6
OV	KDELR3 →	+0.918	+0.333	.007	.008	3	5
BRCA	RSPRY1 →	+0.454	+0.346	<.001	<.001	3	5
BRCA	NUTF2 →	+0.441	+0.465	<.001	<.001	3	4
OV	POLR2C →	+0.407	+0.335	.008	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,239 associations by consensus.

GLG1 vs ITFG1 — OV

Explore this scatter interactively →